21 Best Probiotics for Men: Top Probiotic Supplements in 2024

Best Probiotics for Men

Most health professional agree that you should take a probiotic for men on a daily basis. Your gut microbiome is integral not only to your digestive system but your systemic health at large, and daily supplement helps to ensure that you get the probiotics you need and are resistant to imbalances.

Choosing the best probiotic for men can be a daunting process. Probiotic supplements are a multibillion-dollar industry, and there are hundreds of products on the market all vying for your business. In order to help you pare down your options to products that are established and effective and enjoy high customer satisfaction levels, we have reviewed hundreds of products for men’s gut health.

Without further ado, here are our top picks for 2024:

  1. Probiology Gut+
  2. Biotics 8
  3. Elm & Rye Probiotics
  4. Physician’s Choice Probiotic
  5. Renew Life Ultimate Flora Extra Care Probiotic
  6. California Gold Nutrition Probiotics
  7. Now Foods Probiotic-10
  8. Florastor Daily Probiotic Supplement
  9. GNC Probiotic Complex
  • The Vitamin Shoppe Ultimate 10+ Probiotics
  • Align Probiotic
  • MegaFood MegaFlora 7-Day Intensive Probiotic
  • Silver Fern Ultimate Probiotic
  • New Chapter All-Flora Probiotic
  • OMNi-BiOTiC AB 10
  • HUM Gut Instinct
  • Ancient Nutrition SBO Probiotics Men’s Capsules
  • Culturelle Digestive Daily Probiotic
  • Garden of Life Dr. Formulated Probiotics Once Daily Men’s
  • Jarrow Formulas Jarro-Dophilus Gut Calm
  • Klaire Labs Ther-Biotic Complete

A Closer Look at the Top Probiotics for Men


In the reviews ahead, we’ll take an in-depth look at our number one and number two probiotic pills for men. We’ll then round out our rankings with a brief overview of the other top probiotics for guys.

1. Probiology Gut+

Probiology Gut+

Probiology is in our opinion the best probiotic brand, and Gut+ is the most-effective probiotic for men. The old adage that you get what you pay for is absolutely true when it comes to probiotics. Many brands make CFU guarantees, but the caveat is that the count is guaranteed at the time of manufacturing or at the time of taking the product.

The issue is that many probiotics do not make it beyond the stomach let alone the large intestine. Gut+ is different, and the reason for this is the patented MAKtrek® Bipass Technology. This process involves the use of natural marine polysaccharides, which are derived from brown seaweed, to protect the good bacteria as it makes its way through your system.


  • Prebiotic and probiotic formula
  • Formulated to survive digestion
  • Four strains and 40 billion CFUs
  • 100% satisfaction, 60-day money-back guarantee
  • Made in the U.S. at an FDA-approved and GMP-certified facility



  • Bifidobacterium lactis: helps digestion and absorption and strengthens and seals gut lining.
  • Brown seaweed extract: protects the prebiotics so that survive digestion.
  • Fructooligosaccha: a natural prebiotic formula that feeds the good bacteria.
  • Lactobacillus acidophilus: helps to balance the gut bacteria and reduces IBS symptoms.
  • Lactobacillus paracasei: improves immunity and skin health and is an anti-inflammatory.
  • Lactobacillus plantarum: Improves regularity and stops upset stomach, bloating, and cramping.


Probiology Gut+ is developed as a shelf-stable probiotic, which means that it does not require refrigeration and will last up to two years. The brown seaweed extract is added during the patented manufacturing process and essentially serves as a shield that protects the bacteria as it moves through your digestive system. This helps to ensure that a high count makes it to your small intestine alive.

While there is still some debate on the matter, most scientists agree that a small number of strains chosen for a specific purpose is better than formulas that combine many strains. The Bifidobacterium and Lactobacillus strains used here are among the most clinically researched, and they all play important roles in a well-functioning digestive system. The formula is dairy, gluten and soy free and contains no preservatives. It does have a gelatin capsule, and we would love to see a switch to a veggie capsule.

Dosage and Usage:

Probiology Gut+ is sold in bottles that contain 60 capsules, which is a one-month supply. Two capsules per day is the recommend dosage, and Probiology advises taking one capsule in the day and one in the evening. This is interesting as there is still some debate among doctors, nutritionists, and the like concerning whether it is better to take it early or late. This sidesteps the issue.

Although the label does not specific it, we recommend taking one capsule in the morning at least 20 minutes prior to eating and taking the second capsule at least 20 minutes prior to your final meal of the deal.

Pricing, Shipping and Refund Policy

The retail price for Probiology Gut+ is $74.99. The usual price is $59.99, and there are bulk discounts available. A three-bottle order costs $119.99, and a five-bottle order costs $179.99. Shipping is free anywhere in the world with all orders, and there is often a promotional code available that gives you an additional 10% off.

You have 67 days from the date you receive your first shipment to request a refund with no questions asked. Probiology does require to return all opened and opened bottles at your own cost, but once it receives that return, it will refund you 100% of the original order price.

>Want an even better deal on Probiology Gut+? Click here for an exclusive special!

2. Biotics 8

Biotics 8

Biotics 8 is developed by Bauer Nutrition, which is among the most established and trusted names in the health and wellness industry. This multi-strain formula includes 10 strains that Bauer has purposefully selected for gut and overall health. Biotics 8 is milder than Probiology Gut+ and other products to make our list, but it is strong enough and has a robust formula that includes digestive enzymes and other substances chosen to support gut heath, boost the immune system, bolster your mood, and so forth.


  • Well-rounded dietary supplement
  • Prebiotic and probiotic formula
  • Features digestive enzymes and dietary fiber
  • 10 strains and 2 billion CFUs in a veggie capsule
  • 100% satisfaction, 60-day money-back guarantee


  • Not suitable for vegans or vegetarians
  • Only available online through official website


  • Amylase: a digestive enzyme that helps you digest food and absorb nutrients.
  • Bifidobacterium fermentum: reduces cholesterol and bolster the immune system.
  • Bifidobacterium longum: stabilizes gut microbiome and alleviates digestive distress.
  • Bifidobacterium bifidum: prevalent probiotic bacteria integral to human digestion.
  • Fructooligosaccharides: fiber used to feed the good bacteria and aid in digestion.
  • Lactobacillus acidophilus: helps to balance the gut bacteria and reduces IBS symptoms.
  • Lactobacillus casei: used to prevent diarrhea and other digestive issues.
  • Lactobacillus paracasei: associated with immune health, respiratory health, and bowel function.
  • Lactobacillus rhamnosus: prevalent probiotic bacteria integral to digestion and immunity.
  • Lactobacillus plantarum: helps to mitigate bad bacteria in the gut.
  • Lactobacillus fermentum: important to digestion starting with good oral health.
  • Lipase: used by the intestines to break down fats in foods.
  • Inulin: a starchy substance that feeds the good bacteria and aids in digestion.
  • Protease: enzyme that breaks down proteins in digestion but also on the skin.
  • Saccharromyces Boulardii: a probiotic that helps to balance responses within the gut.


Biotics 8 is a product that has been around for a long time. In fact, the original formula used vitamins, minerals, and plant extracts, but it was reintroduced with a probiotic formula when that proved to be more effective. Unlike Probiology Gut+, this is a dairy product, and while that makes the product unsuitable for people who are lactose intolerant, it allows for a more robust probiotic profile. This product is also made with a veggie capsule rather than a gelatin capsule, which means that the product is suitable for vegans and vegetarians.

Dosage and Usage:

Bauer sells Biotics 8 in bottles that contain 60 capsules, which is a one-month supply. The label recommends taking two capsules daily and that if you need time to adjust, you should take one capsule daily for three to four days. Then, take three capsules for the same number of days before moving on to the normal dosage. There is no scheduling recommendation, so you should feel free to take both in the morning or to take one in the morning and one in the evening. However you take them, it is best to do so with water and at least 20 minutes prior to eating.

Pricing, Shipping and Refund Policy

The retail price is $74.99 a bottle. The usual price is $59.99, and shipping is free on all orders. There are bulk discounts as well: three bottles cost $119.99 and five bottles cost $179.99. Like Probiology, Bauer gives you 67 days from the date you receive your order to request a full refund for any reason.

>Click here to try Biotics 8 at a price you will not find anywhere else!

3. Elm & Rye Probiotics

Elm & Rye Probiotics

Elm & Rye is a leading supplement brand. This particular product has been developed by doctors and is endorsed by many medical professionals. While it is not developed or marketed specifically as a daily probiotic for men, it is highly effective as such. This is a single-strain probiotic—Lactobacillus acidophilus—and well worth a look for anybody who prefers that type of probiotic supplement.

4. Physician’s Choice Probiotic

Physician’s Choice is recommended by many doctors and is well known as a brand that makes high-quality dietary supplements but sells them at non-premium prices. At the time of this writing, a one-month supply cost less than $20. Note that this brand makes a wide range of probiotic supplements, and the one we recommend as good probiotics for men is the 60 Billion Probiotic.

5. Renew Life Ultimate Flora Extra Care Probiotic

Renew Life as a brand is recommended by many doctors as well, and while the company does not spend as much on marketing as some of its competitors, it does get visibility in that it is available in practically every major big-box store and pharmacy in the U.S. Extra Care is a delayed-released formula, and this product has undergone more clinical trialing than almost all other probiotic supplements for men.

6. California Gold Nutrition Probiotics

California Gold Nutrition not only makes affordable probiotics for men but ensures that they are suitable for men with special dietary needs. They are safe for vegans and vegetarians and free of gluten, fish, yeast, sugar, and much more. CGN offers a wide range of probiotic supplements, which are mostly distinguished by their CFU count, which is useful for men who need to acclimate to the higher counts.

7. Now Foods Probiotic-10

Now Foods is an American brand that has been around since the 1970s, and it has been popular regionally throughout the U.S. for a long time, but it is really the last 20 years or so thanks to Amazon and other major online retailers that is has become so prevalent. This is a top probiotic for men’s digestive health, and it is very inexpensive and can be even cheaper if you subscribe through Amazon.

8. Florastor Daily Probiotic Supplement

Florastor is a respected and established brand, and this single-strain product is among the most recommended probiotics by doctors. It is sold at a higher price point than similar products, and customers should note that this is a lactose-based product that contains soy. But if those aspects are not an issue for you, this is a strong product that is used successfully by millions of men.

9. GNC Probiotic Complex

GNC is an established and well-known American brand with an international presence. It may be best known as a retailer of dietary supplements, but it has its own line of products. The GNC Probiotic Complex is strong and popular if not a bit pricey, but there a number of discounts available, such as 50% off on the second box if you purchase a two-month supply either online or in store.

10. The Vitamin Shoppe Ultimate 10+ Probiotics

Vitamin Shoppe is a popular brand known for vitamins and probiotics for men. The brand is available online but also sold through most major retailers in the U.S. This product is safe for vegans and vegetarians. It is a strong option for digestive and immune system health, and it is also notable as being a highly recommended product by doctors to people with allergies, asthma, COPD, and so forth.

11. Align Probiotic

Align is a Canadian brand that is popular throughout North America. This is a pure- and single-strain supplement—Bifidobacterium longum 35624—designed specifically as a probiotic for IBS. However, this a well-rounded probiotic for men that is effective and well-priced. The company even publishes a schedule that new customers can use to set their expectations and gauge their progress.

12. MegaFood MegaFlora 7-Day Intensive Probiotic

If you prefer a multi-strain supplement with a very high CFU count, then the MegaFlora 7-Day Intensive Probiotic is among the best probiotics for men’s gut health. This is in our opinion a probiotic to be used as needed perhaps if you are taking antibiotics or are ill or recovering from food poisoning. It can be taken as a daily probiotic, but the average consumer will view it as too expensive for that.

13. Silver Fern Ultimate Probiotic

Ultimate Probiotic from Silver Fern is among the best probiotics on the market and has undergone extensive clinical trials to ensure CFU survivability, which is not something all brands do. It is a bit on the pricey side but is another excellent option to consider for men with particular diet restrictions.

14. New Chapter All-Flora Probiotic

All-Flora Probiotic from New Chapter is a strong choice among men’s probiotic vitamins. This formula includes prebiotics and probiotics but also postbiotics, such as vitamin B, vitamin K, amino acids, antimicrobial peptides, and short-chain fatty acids. Men who take multiple supplements daily will want to ensure that you are not exceeding the tolerable upper intake level.

15. OMNi-BiOTiC AB 10

This is among the best male probiotics but falls down our list a bit since it is relatively expensive. It is also among the most clinically trialed products as in not just the strains but the supplement itself. The higher price comes with territory with such products, and you may prefer that peace of mind.

16. HUM Gut Instinct

This supplement is a vegan probiotic for men that was developed with an emphasis on skin health. Many men have eczema and other skin disorders that are a result of an imbalanced gut microbiome. This formula is designed to correct those issues by targeting the bad bacteria that causes them, but it is also a well-rounded and affordable probiotic that you should feel comfortable taking as a daily supplement.

17. Ancient Nutrition SBO Probiotics Men’s Capsules

Ancient Nutrition is the brand founded by Dr. Josh Axe who is the author of the Keto Diet and The Gut Repair Cookbook. There are number of probiotic supplements made by this brand. The probiotic for men is the best choice for most, but Gut Restore is a solid option if you are experiencing digestive distress. SBO Ultimate is also a good choice if you find that you want a stronger formula.

18. Culturelle Digestive Daily Probiotic

The Culturelle Digestive Daily Probiotic is an effective probiotic supplement for men that has 10 billion CFUs and which is cheaper than most of the products that we have included in this ranking. If you are a man in good health who just wants a cheap option as a daily probiotic, this product is a solid choice.

19. Garden of Life Dr. Formulated Probiotics Once Daily Men’s

This is a probiotic developed by a group of doctors specifically for men and with a focus on colon health. It features 15 strains, including Lactobacilli and Bifidobacteria, and has a guaranteed 50 billion CFUs. The dosage is just one easy-to-swallow capsule a day, which you should take in the morning.

20. Jarrow Formulas Jarro-Dophilus Gut Calm

This is one of the most popular and top-rated probiotics for men. It is affordable and vegan and vegetarian friendly. It features three patented and clinically trialed strains developed to calm the gut, and this is a good option if you require a probiotic in order to avoid digestive distress.

21. Klaire Labs Ther-Biotic Complete

Ther-Biotic is a solid choice as a men’s probiotic that is a bit pricey but suitable for guys with dietary restrictions. What perhaps distinguishes this product most is that you can purchase it in powder form. This is not common and a great choice for males who have trouble swallowing pills.

Why Men Need Probiotics

Probiotics for men are important because the good bacteria are necessary to keep the gut microbiome balanced, which improves digestive health and thus bolsters systemic health. You can acquire the necessary bacteria through your diet, but many men do not get enough and are prone to imbalances due to their overall diet, stress, and a wide range of other issues.

A potent probiotic not only improves your digestive health but supports mental health, improves your metabolism, bolsters your immune system, helps you lose weight or maintain it, supports prostate health, plays a role in maintaining optimal testosterone levels, reduces allergy and asthma symptoms, helps with ulcers, and much more.

Probiotics for Men vs. Probiotics for Women

There is still somewhat of a debate in the scientific community whether probiotic formulas should be tailored to a particular gender, and many of the products that we have featured here are actually developed for all adults and not specifically men. That said, many of the products for men have been clinically trialed extensively with men as the subjects, and there are targeted products for men, such as a probiotic for testosterone support or a probiotic for men’s weight loss.

The best probiotics for women will often have formulas that support the vaginal flora and help to prevent yeast infections. Although many men are understandably reticent to take such supplements, those same bacteria are found in the digestive systems of men, and those products are perfectly fine to take by men but perhaps not optimal.

Probiotics and Side Effects

The microbes found in a men’s probiotic are naturally occurring within the body and generally do not cause side effects. People who have compromised immune systems can potentially develop an infection from probiotics, but they are entirely safe for the general population.

A small number of men are sensitive to probiotics. If you are sensitive or you take a large quantity, you could experience mild symptoms, such as an upset stomach, bloating, gas, and diarrhea. However, even people sensitive to probiotics can acclimate to even the strongest products and eventually handle high CFU counts.

Probiotics With Other Dietary Supplements and Medications

It is safe to take natural probiotics for men with other dietary supplements. The important thing is that you track all of the ingredients ingested and ensure that you are not exceeding safe levels. You can take probiotics with medicines, and it is often recommended. However, you should check with your doctors and pharmacist to determine the optimal way to schedule your medicine and supplement doses.

Related: 12 Best Supplements for Gut Health

How We Selected the Best Probiotics for Men

Our team started with an extensive list of probiotics targeted at men but also people in general. We then vetted the brand and considered the longevity of the product, whether it had ever been rebranded, the ingredients, and whether those ingredients or the product itself had been clinically trialed.

For the products that remained, we collected data from the available verifiable customer reviews. An extensive review beyond that point was limited to our top two products, but we are confident that the other 20 are safe supplements that will be effective for the average man.

Frequently Asked Questions

1. Are There Signs That You Need Probiotics?

Digestive distress is the most prevalent indication that you should take a probiotic supplement, and this can take many different forms, including gas and bloating, abdominal pain, and stool changes. An imbalanced gut microbiome can also suppress your immune system, so frequent illness is a sign as well.

Imbalanced gut bacteria can also cause skin conditions and worsened allergy and asthma symptoms. Also, if you are taking antibiotics or have recently suffered food poisoning, it is generally recommended that you take probiotics in order to restore the balance in your digestive system.

2. Is It Safe to Take a Probiotic Every Day?

The general answer to this question is yes, it is safe take probiotics on a daily basis, and many doctors, nutritionists, and other experts recommend daily usage as an effective way to maintain a balanced gut. There is no chance to overdose on probiotics or become dependent on them. Sone people are sensitive and thus may have to acclimate to higher doses, and of course, people with serious health conditions should discuss using probiotics with their doctor.

3. Can You Take Too Much Probiotics?

No in the sense that taking too much probiotics will not cause serious side effects or death. But the answer is yes from the perspective that you could cause uncomfortable symptoms, such as gas, bloating, upset stomach, diarrhea, and so forth. The exception here is immunocompromised people who should consult with a physician before taking probiotics.

4. Does the CFU Count Matter?

A colony forming units count indicates the number of live bacteria in a probiotic supplement. The higher the number, the more live bacteria that will reach your lower intestine. The general rule for adults is that the CFU count should be between 1 billion and 10 billion CFUs. You may notice that many of the best probiotics for men have much higher counts than that, and that is effective as long as you are acclimated to that strength and are in good general health.

5. I Eat Yogurt. Isn’t That Enough?

Yogurt is an excellent source of probiotics. There are other foods as well, such as pickles, sauerkraut, kimchi, sourdough bread, and some cheeses. You may be getting the probiotics you need from yogurt, but be mindful that not all yogurt has live strains or a high CFU. Taking a men’s probiotic ensures that you do get enough so that you can enjoy your yogurt without worrying about it.

6. Do Probiotics Need to Be Refrigerated?

Foods that contain probiotics do require refrigeration. Most probiotic pills for men are shelf stable and thus do not require refrigeration. However, some probiotics do require refrigeration. This will be indicated on the label, and these products are shipped in special cooled containers.

7. Should You Take Probiotics in the Morning or at Night?

The important thing is that you take probiotics on an empty stomach at least 20 minutes prior to eating. We generally advise taking a probiotic supplement in the morning prior to eating your breakfast, but research has shown benefits to taking a probiotic at night as well. You may want to consider taking smaller doses prior to all of your meals, which many people have great success with.

8. Which Probiotic Foods Should You Eat?

Yogurt and sauerkraut are excellent choices, but be aware that not all of the products available at your locally grocery will actually have live bacteria strains. Many of the best options are fermented, such as pickles, olives, apple cider vinegar, kimchi, kombucha, natto, miso, fermented cheese, and so forth.

Final Thoughts

Most doctors agree that all men should take a daily probiotic as a way to supplement their diets and ensure that their gut microbiome remains balanced. If you want to ensure that you are buying the best probiotic for men without much effort, Probiology Gut+ and Biotics 8 are excellent choices. But all of the products we have listed here are good quality probiotics, and you should feel confident in all of them.

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